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Nolvadex (tamoxifen citrate)

This drug is used as a first line defense against breast cancer. In the late 80s, Dan Duchaine speculated that it could also be used by bodybuilders to halt the cialis development of another type of tumor in the mammary gland, Gynocomastia. He introduced this find to the Steroid -using-community in his "Contest Prep" issue of the Underground Steroid Handbook Update Newsletters (the contest prep-issue was actually 3 issues in one, for those who had a subscription to the newsletter).

Nolvadex is commonly referred to in quite a few ways: as a SERM (Selective Estrogen Receptor Modulator), as an anti-estrogen (that is actually incorrect, as we will later see), and finally as a triphenylethylene. I happen to stick with calling Nolvadex a SERM, because out of my three options, it happens to be correct (as we know that calling it an anti-estrogen is incorrect), and pronounceable (as we know that I have no idea how to say "triphenylethylene"). Selective estrogen receptor modulators (SERMs) act as either estrogen receptor agonists or antagonists in a tissue-selective manner, lets see what that means to us.

Nolvadex actually has quite a few applications for the steroid using athlete. First cialis and foremost, its most common use is for the prevention of gynocomastia. Nolvadex does this by actually competing for the receptor site in breast tissue, and binding to it. Thus, we can safely say that the effect of tamoxifen is through estrogen receptor blockade of breast tissue (1), especially since total body estradiol increases with use of tamoxifen. Clearly, if you are on a cycle which includes steroids which convert to estrogen, you may want to consider nolvadex as a good choice to run along side them.

Nolvadex Cycle

Nolvadex, however, is not the most potent ancillary compound we can use on a cycle, but it is probably the safest considering it doesn't actually reduce estrogen in your body keeping some estrogen floating around could have many benefits on muscle growth, as well. Estrogen is also important for a properly functioning immune system, and not only that, but your lipid profile (both HDL and LDL) should also show marked improvement with administration of tamoxifen (4). Many bodybuilders actually use this stuff during their cycle for the health benefits provided by it. If, however, you are preparing for a bodybuilding contest, you need to use something which will suck most (if not all) of the estrogen out of your body. I am speculating that you may be able to use Nolvadex for the majority of a contest prep cycle, to keep yourself relatively healthy, and then switch over to Letrozole for the last 8 weeks.

Nolvadex also has some important features for the steroid using athlete. In hypogonadic and infertile men given nolvadex, increases in the serum levels of LH, FSH, and most importantly, testosterone were all observed (2)(3). The best (rough) estimate I can give you from my research is that 20mgs of Nolvadex will raise your testosterone levels about 150% (5). and this would of course greatly aid post-cycle-recovery. What this means to us is that if you take Nolvadex after a cycle, when you are trying to raise your levels of testosterone, LH, and FSH back to normal, it will greatly aid recovery. In fact, if I were limited to just one compound to aid me in post-cycle-recovery, Nolvadex would be my choice. If you want a comparison, it would require 150mgs of Clomid to accomplish that type of elevation in testosterone, but nolvadex also significantly increased the LH (Leutenizing Hormone) response to LHRL (5), after 6 weeks.

Some of the more harsh ancillary levitra compounds available today will give you a more "dry" look that nolvadex cant, but nolvadex is simply safer to use in long (over 16 week) cycles.

Nolvadex Side Effects

Unfortunately, Nolvadex isn't perfect. Anecdotally, it has been linked to reduced gains in some bodybuilders. This isn't due, as previously thought, to its reducing estrogen levels (which it doesn't), but rather to its ability to possibly reduce IGF kamagra (Insulin -like-Growth-Factor) levels, which are important for muscle growth.

To Buy Nolvadex Online

Personally, I've had many successful cycles with Nolvadex as well as without, but I can certainly testify to its effectiveness in preventing gynocomastia. Back in the late 90s I purchased 30 tabs of 10mg Nolvadex for $30, and recently I have found it for much less on various internet sites. Its well worth the money.

Nolvadex References:

Klin Padiatr. 1987 Nov-Dec;199(6):389-91.

Stimulation of calcitonin secretory capacity by increased serum levels of testosterone in men treated with tamoxifen. Int J Androl. 1987 Dec;10(6):747-51.

Hormonal changes in tamoxifen treated men with idiopathic oligozoospermia Exp Clin Endocrinol. 1988 Dec;92(2):211-6.

2 Bruning PF, Bronfer JMG, Hart AAM, Jong-Bakker M, tamoxifen, serum lipoproteins and cardiovascular risk, Br. J. Cancer 1988 Oct, 58 (4) 497-9

Fertil Steril. 1978 Mar;29(3):320-7.





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Nolvadex Side Effects Center

Prescribing Information

For Patients

Nolvadex (tamoxifen citrate) is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients. Most common side effects include hot flashes, nausea, leg cramps, hair thinning, or headache. A loss of sexual ability/interest may occur in men. Other less common side effects may also occur.

The recommended daily dose of Nolvadex for patients with breast cancer is 20-40 mg per day, in tablet form. Patients taking anastrozole or letrozole should not take Nolvadex as serious interactions could occur. SSRI antidepressants and cimeditdine may affect how Nolvadex works. Patients taking coumarin-type anticoagulants should be closely monitored. There may be risks to the fetus if Nolvadex is taken by pregnant women, however the benefit of the drug may warrant its use despite the potential risks. Nolvadex has been reported to inhibit lactation. It is not known whether the medication is passed through breast milk, but because of the potential risks for the fetus, women who are taking Nolvadex should not breast feed.

Our Nolvadex Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.



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Generic Tamoxifen Tablets - Product Information

Generic Tamoxifen is a medicine used for the treatment and prevention of breast cancer in men and women.

It is also recommended for other conditions, such as infertility in women and mania in bipolar disorder. Generic Tamoxifen Tablets, a nonsteroidal antiestrogen, is used for oral administration.

Name of Drug

Generic Tamoxifen: We supply Tamtero manufactured by Hetero Drugs Ltd.

Generic Tamoxifen is sometimes also referred to as:Each 10 mg tablet of Tamtero contains 15.2 mg of tamoxifen citrate which is equivalent to 10 mg of tamoxifen.

Manufacturer Of Generic Tamoxifen Tablets

Hetero Drugs Ltd.

website: hetero.com

Active Pharmaceutical Ingredient in Generic Tamoxifen

The active pharmaceutical ingredient present in Generic Tamoxifen Tablets (Tamtero) is Tamoxifen Citrate.

Uses of Generic Tamoxifen Tablets

Generic Tamoxifen (Tamtero Tablets| is used for:

Generic Tamoxifen is effective in the treatment of metastatic breast cancer in women and men.

Generic Tamoxifen is used for the treatment of early and advanced ER+ (estrogen receptor positive) breast cancer in pre- and post-menopausal women.

Generic Tamoxifen is used also for the treatment of male breast cancer.

Generic Tamoxifen is approved by FDA to prevent breast cancer in women which are at high risk to develop this disease.

Generic Tamoxifen helps to prevent the development of cancers in the other breast.

Generic Tamoxifen is an alternative to oophorectomy or ovarian irradiation.

Generic Tamoxifen is used to treat infertility in women with anovulatory (irregular menstrual cycles, no ovulation) disorders.

Generic Tamoxifen is effective in treatment of mania in patients with bipolar disorder.

Generic Tamoxifen Dosage

Your Generic Tamoxifen dosage will depend on whether the medication is being used to treat or prevent breast cancer, how severe the breast cancer is, and whether other medications are being taken. A starting dose of 20 mg is common when preventing breast cancer. The Generic Tamoxifen dosage can range from 20 to 40 mg a day when used to treat breast cancer.

Generic Tamoxifen is prescribed for metastatic breast cancer for varying lengths of time. It is depending on the cancer's response to the treatment.

Generic Tamoxifen is usually prescribed for 5 years, if it is used as adjuvant therapy for early-stage breast cancer. The recommended dose is 20 mg a day - irrespective of weight and age. When taken for 5 years, Generic Tamoxifen reduces the risk of developing a second primary cancer in the other breast and the the chance of the original breast cancer coming back in the same breast or somewhere else. For the treatment of infertility: 10-40 mg a day in days 3-7 of the menstrual cycle. Bipolar patients should only use Generic Tamoxifen after consulting a doctor, please follow exactly your doctor's recommendation! Commonly prescribed for bipolar disorder are 20 mg twice daily increasing up to 40 mg twice daily.

What To Do In Case Of A Missed Dose

If you miss your regular dose of Generic Tamoxifen, receive it as soon as possible. If the current time is too close to the time for your next dose, skip the missed dose and then return to your regular dosing schedule. Do not take a double dose at once.

Drug Class and Mechanism

Generic Tamoxifen is an antiestrogen.

Estrogen can promote the growth of breast cancer cells. Some breast cancers are classified as estrogen receptor-positive (also known as hormone sensitive), which means that they have a protein to which estrogen will bind. These breast cancer cells need estrogen to grow. Generic Tamoxifen works against the effects of estrogen on these cells. It is often called an antiestrogen or a SERM (Selective Estrogen Receptor Modulator).

Studies have shown that tamoxifen is only effective in treating estrogen receptor-positive breast cancers. Therefore, the tumor’s hormone receptor status should be determined before deciding on treatment options for breast cancer.

Storage Instructions for Generic Tamoxifen Tablets

Generic Tamoxifen should be stored at temperatures between 68 and 77 degrees F (20 and 25 degrees C) in a tightly closed and light-resistant container. Keep away from moisture, heat and light. Do not store the drug in the bathroom. Do not use the tablets after the expiration date. This date is printed on the label. Keep the drug out of the reach of children and animals.

Warnings and Precautions when using Generic Tamoxifen Tablets

Possible serious side effects are reported such as blood clots, uterine cancer, strokes and cataracts. The benefits of Generic Tamoxifen are established and far outweigh the possible potential risks.

Warning on pregnancy and breast-feeding

Generic Tamoxifen may cause harm to the human fetus. Avoid becoming pregnant while you are receiving Generic Tamoxifen. It is also necessary to avoid becoming pregnant for 2 months after you stop receiving Generic Tamoxifen. If you suspect that you may be pregnant, contact your doctor. You will need to discuss all the benefits and risks of receiving Generic Tamoxifen during the pregnancy. It is not known if Generic Tamoxifen is found in female breast milk, therefore you ought to avoid breast-feeding while receiving this drug.

Side Effects of Generic Tamoxifen

The most common side effects of Generic Tamoxifen Tablets are listed below. Consult with your doctor if any of these side effects persist or become bothersome:

weight gain

nausea

hot flashes

abnormal menstrual cycle

joint pain

leg cramps

pain in muscles

constipation

tiredness

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STEROID PRODUCT NAME: Sustan 250, Sustanon

SUBSTANCE: Test.Mix.

CONTENT: 10ml Vial/[250mg/1ml]

Sustanon Information

Active Life: Approx. 21 days

Drug Class: Anabolic/Androgenic Steroid (for injection)

Average Dose: 250-1000 mg/week (males only)

Water Retention: Yes

High Blood Pressure: Yes

Liver Toxic: Low

Aromatization: Yes

DHT Conversion: Yes, high

Decrease HPTA function: Yes, severe

What does Sustanon 250 contain

Sustanon 250 is an oil-based injectable Testosterone blend. Sustanon developed by the international drug firm Organon. The substance typically contains four different Testosterone esters: Testosterone propionate (30 mg); Testosterone phenylpropionate (60 mg); Testosterone isocaproate (60mg); and Testosterone decanoate (100 mg), although a lower dosed version is also produced. An intelligently "engineered" Testosterone, Sustanon is designed to provide a fast yet extended release of Testosterone. The propionate and phenylpropionate esters are quickly utilized, releasing into circulation within the first four days. The remaining esters are much slower to release. Sustanon stayes active in the body for about two and three weeks (respectively). This is a big improvement of Sustanon from standard Testosterones such as cypionate or enanthate, which provide a much shorter duration of activity, and a more variable blood level.

As with all Testosterone products, Sustanon is a strong anabolic with pronounced androgenic activity. It is most commonly used as a bulking drug, providing exceptional gains in strength and muscle mass. Although it does convert to estrogen, as is the nature of Testosterone, Sustanon injectable is noted as being slightly more tolerable than cypionate or enanthate. As stated throughout this book, such observations are only issues of timing however. Blood levels of Testosterone are building more slowly, so side effects do not set in as fast. For equal blood hormone levels however, Testosterone will break down equally without regard to ester. Many individuals may likewise find it necessary to use with this steroid an antiestrogen, in which case a low dosage of Nolvadex or Proviron would be appropriate. Also correlating with estrogen, water retention should be noticeable. This is not desirable when the athlete is looking to maintain a quality look to the physique, so this is certainly not an idea drug for contest preparation. Sustanon 250 Side effects

As Sustanon 250 is a strong androgen, we can expect the typical side effects. This includes oily skin, acne body/facial hair growth and premature balding. The addition of Proscar/Propecia should be able to minimize Sustanon side effects, as it will limit the Testosterone to DHT (dihydroTestosterone) conversion process. Sustanon will also suppress natural Testosterone production rather quickly. The use of HCG (Human Chorionic Gonadotropin) and/or Clomid (clomiphene citrate)/Nolvadex (tamoxifen citrate) may be necessary at the conclusion of a cycle in order to avoid a hormonal crash. Remember though, Sustanon will remain active in the body for up to a month after your last injection was given. Beginning you ancillary drug therapy immediately after the steroid has been discontinued will not be very effective. Instead, HCG or Clomid (clomiphene citrate)/Nolvadex should be delayed two or three weeks, until you are near the point where blood androgen levels after Sustanon cycle are dropping significantly.

Sustanon Dosage

Although Sustanon remains active in the body for approximately three weeks, injections are taken at least every 10 days. An effective dosage ranges from 250mg (one ampule) every 10 days, to 1000mg (four ampules) weekly. Some athletes do use more extreme dosages, but this is really not a recommended practice. When the dosage rises above 750-1000mg per week, increased of Sustanon side effects will no doubt be outweighing additional An benefits. Basically you will receive a poor return on your investment, which with Sustanon can be substantial. Instead of taking unnecessarily large amounts, athletes interested in rapid size and strength will usually opt to addition another compound. For this purpose we find that stacks extremely well with the potent orals Anadrol 50 (oxymetholone) and Dianabol (methandrostenolone). On the other hand, Sustanon may work better with trenbolone or Winstrol (stanozolol) if the athlete were seeking to maintain a harder, more defined look to his physique.



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M1T or Methyl 1- Testosterone . is the methylated adaption of the steroid 1- Testosterone . The adaption was made to make the pro hormone available for oral consumption by inhibiting breakdown in the liver. The characteristics of this pro hormone are that it is highly anabolic while only moderately androgenic and importantly does not convert to estrogen.

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Primolut N Tablets - Product Information

Primolut N tablets contain the active ingredient Norethisterone which is a progestogen with negligible androgenic effects. Primolut N is used for timing of menstruation and to treat disturbances of the monthly bleeding (dysfunctional bleeding), lack of the monthly bleeding (primary and secondary amenorrhoea), premenstrual complaints (premenstrual syndrome), in combination with oestrogen hormone replacement therapy, and endometriosis.

Name of Drug

Manufacturer Of Primolut N Tablets

Manufactured in India by Zydus Cadila in cooperation with Bayer.

Website: www.zyduscadila.com

Active Pharmaceutical Ingredient in Primolut N Tablets

The active pharmaceutical ingredient present in Primolut N tablets is Norethisterone .

Primolut N Tablets - Dosage

Primolut N tablets are to be swallowed whole with a sufficient quantity of water or other suitable liquid. The dosage varies as per indication being treated.

Dysfunctional bleeding(Disturbances of your period):

The recommended dosage of Primolut N is 1 tablet of Primolut N 3 times daily for 10 days. In most cases bleeding will stop within 1 to 3 days, but Primolut N must be taken for the full 10 days. About 2 to 4 days after you stop taking the tablets, withdrawal bleeding will occur.

Primary and secondary amenorrhoea (lack of a period):

Hormone treatment of secondary amenorrhoea can be carried out only after pregnancy has been excluded. The doctor will prescribe the patient an oestrogen (usually for 14 days) before beginning treatment with Primolut N. After which the patient will have to take 1 tablet of Primolut N 1 to 2 times daily for 10 days. Normally withdrawal bleeding occurs a few days after taking the last tablet.

Premenstrual syndrome:

The recommended dosage is one tablet of Primolut N one to three times daily during the 2nd half (luteal phase) of the cycle may relieve or improve premenstrual symptoms such as headaches, depressive moods, water retention, and a feeling of tension in the breasts.

Delaying menstruation:

Monthly menstrual bleeding can be delayed by taking Primolut N. However, this method of delaying your monthly period can be used by you only if you are not at risk of pregnancy during the treatment cycle.

The recommended dosage is 1 tablet of Primolut N two to three times daily for no longer than 10 to 14 days, beginning about 3 days before expected menstruation. Usually bleeding will occur 2 to 3 days after you stop taking the tablets.

Endometriosis:

Treatment with Primolut N should begin between the first and 5th day of the cycle with 1 tablet twice daily. In the event of spotting, the dose can be increased to 2 tablets twice daily. If bleeding stops, dose reduction to the initial dose should be considered. Treatment is to be continued for at least 4 to 6 months.

Missed Dose

The efficacy of Primolut N could be reduced if the patient forgets to take a tablet as directed. The missed dose of Primolut N has to be taken as soon as the patient remember. Only the last missed dose should be taken and then the patient has to continue to take the tablet at the usual time on the next day. Do not take a double dose.

Storage Instructions for Primolut N Tablets

Primolut N tablets should be kept at room temperature, 15-30°C (59-86°F) in a light-resistant, tight container. Keep away from children.

Warnings and Precautions when using Primolut N Tablets

Before using Primolut N tablets please inform your doctor all the medicines that you take including no prescription medications, over the counter medicines and herbal remedies.

Contraindications

Primolut N is contraindicated in patients with any of the conditions listed below. In case any of the conditions appear during treatment with Primolut N, the use of this medication has to immediately discontinued.

Hypersensitivity to the active ingredient Norethisterone or to any of the substances present in the medication.

Known or suspected pregnancy

Lactation

Thromboembolic disorders, thrombophlebitis ,cerebral apoplexy or a history of these conditions

Arterial and cardiovascular disease present in the patient or history of the same (e.g. myocardial infarction, cerebrovascular accident, ischemic heart disease)

Diabetes mellitus with vascular involvement

Presence or history of severe hepatic disease as long as liver function values have not returned to normal

Presence or history of liver tumors (benign or malignant)

Known or suspected sex hormone-dependent malignancies

Dubin-Johnson syndrome

Rotor syndrome

Missed abortion

Undiagnosed vaginal or urinary bleeding

Undiagnosed breast pathology

Primolut N and Pregnancy

Use of Primolut N tablets during pregnancy is contraindicated. Primolut N may affect the developing baby if it is taken during pregnancy. Primolut N may provoke signs of virilization in female fetuses if administered during the hormone-sensitive stage of somatic sexual differentiation. Primolut N should also not be used during lactation.

Primolut N Overdose

Inadvertent intake of a large dose of norethisterone (Primolut N) did not result in a risk of acute adverse effects as per acute toxicity studies conducted.

Side Effects of Primolut N Tablets (Norethisterone)

The side effects reported by users of Primolut N are abnormal vision, nausea, headache, fluid retention, migraine, shortness of breath and hypersensitivity reactions (e.g rash, hives). Normally the side effects are more common during the first months after beginning treatmet with Primolut N but subside with the duration of treatment. The side effects listed below although not reported for Primolut N, have been associated with the use of other progestogens:

anaphylaxis and anaphylactoid like reactions, thrombophlebitis, pulmonary embolism, nervousness, problems with sleeping, drowsiness, tiredness, depression, dizziness, tremor pre-menstrual type depression, hives, itchiness, rash, acne, hirsutism, hair loss, sweating, irregular uterine bleeding, spotting and lack of menstruation, breast tenderness and discharge, changes in cervical excretions and secretions, high fever, Cushing's syndrome, weight gain, moderate elevation of blood pressure, transient elevation of certain liver enzymes, elevations of serum calcium and potassium levels, increases in white cell and platelet counts.

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